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The reverberations from Thursday's presidential debate continue, alongside consequential Supreme Court rulings.

On Wednesday, the U.S. Supreme Court upheld laws in roughly half the states that ban transgender medical care for minors. The vote was 6-to-3, along ideological lines.

A new report from a left-leaning Center on Budget and Policy Priorities finds that upcoming changes to Social Security will amount to a "45-mile trip for some 6 million seniors."

The adventures of a precocious 6-year-old and his stuffed tiger debuted on November 18, 1985. NPR's Renee Montagne spoke with the comic strip's editor, Lee Salem, in 2005.

NPR asks Michelle Bercovici, an employment lawyer who mostly represents federal employees, about what the Trump administration's offer to almost all federal workers to resign by Feb. 6 means for them.

The UNAIDS annual report warns that Trump-era HIV funding cuts could lead to 6 million more infections and 4 million deaths by 2029 — as low-income countries struggle to fill the gap.

Janice Burgess, the Nickelodeon television executive who oversaw shows like Blue Clues, Little Bill, and The Backyardigans, has died at 72. She's remembered for inspiring kids' sense of adventure.

Colorado has been the talk of college football, but they were beat by the Oregon Ducks 42-6. NPR's Michel Martin talks to Washington Post columnist Kevin Blackistone, who appears regularly on ESPN.

With former President Trump's announcement that an indictment for his role in the Jan. 6 attack on the Capitol is coming, tension on the campaign trail shows the tightrope GOP candidates must walk.

Artemis II, the first crewed mission to the Moon in more than 50 years, is set to launch as early as 6:24 p.m. Wednesday.