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Missouri's top race is an open contest for U.S. Senate following the retirement of Republican Roy Blunt.

Two top aides have left Sen. John McCain's presidential campaign, which has been struggling in the polls and with fundraising. The move could affect how the Republican field is shaping up.

Before Monday's Virginia Tech deaths, the deadliest campus shooting in the United States was at the University of Texas on Aug. 1, 1966. Firing from the top of a tower on campus, Charles Whitman killed 16 people and injured 31. An eyewitness looks back.

Should she secure the Democratic nomination, Vice President Kamala Harris would join a short list of female candidates from major parties to top a presidential ticket.

It's like the start of a bad joke: a vegan, a gluten-free and a paleo walk into a bar — except it's your house, and they're gathered around the Thanksgiving table. Don't panic — we've got recipes.

NPR Music celebrates the alt-rock heroes, Hollywood idols, Pulitzer-winning composers, jazz luminaries, cult legends, bold activists, old masters and rising stars the world lost this year.

Pennsylvania, Georgia, Nevada and Arizona come into focus in final days. Plus: where things stand in seven other Senate contests.

A top ally to House Minority Leader Nancy Pelosi, the California Democrat announced Monday that he will not seek re-election after serving in Congress for 40 years.

There have been 40 consecutive drawings since the last time someone won Powerball's top prize on New Year's Day. The jackpot ranks as the eighth largest in U.S. lottery history.

As part of its new marketing campaign, the beverage giant is printing popular first names on labels of Coke, Diet Coke and Coke Zero. But already, there's a backlash from people left feeling excluded.